Peyronie’s Disease Treatment in Miami

There is no single right treatment for Peyronie’s disease — the best option depends on how much your erection curves, whether you also have erectile dysfunction, and whether the disease has stabilized. Dr. Gheiler evaluates the plaque and the curvature, then matches the treatment to the man: non-surgical injections for some, surgery for others.

Peyronie’s bends the erection away from straight — Xiaflex® can reduce the curve.

Xiaflex® (collagenase): reducing curvature without surgery

Xiaflex (collagenase clostridium histolyticum) is the only FDA-approved medication for Peyronie’s disease. It is injected directly into the plaque over a series of treatment cycles to break down the collagen that causes the curve, gradually reducing the curvature. It is an option for men with a stable, palpable plaque and meaningful curvature who want to improve the bend without an operation — particularly those whose erections are still adequate. Dr. Gheiler will tell you honestly whether your curvature and plaque make you a good candidate for injections.

Xiaflex safety — FDA boxed warning. Xiaflex carries the FDA’s most serious safety warning: in a small number of men, the injections have caused corporal rupture (penile fracture) or other serious injury to the penis, including hematoma, some requiring surgical repair. For this reason, Xiaflex for Peyronie’s disease is available only through a restricted FDA program (REMS) and must be administered by a certified physician. Dr. Gheiler will review these risks with you before any injection cycle, along with the precautions that reduce them.

When Peyronie’s comes with erectile dysfunction: the penile implant

When Peyronie’s disease occurs together with erectile dysfunction — which is common — a penile implant is, for appropriately selected patients, the most consistently effective option when other treatments have failed: it straightens the curvature and addresses the erectile dysfunction in a single operation. Dr. Gheiler corrects the curve at the time of implant placement — placing the AMS 700 implant through his Concealed-Scar Scrotal Technique™ — using manual remodeling for milder curves and additional straightening techniques for more severe cases. Because he performs 400+ implant procedures a year, he handles the added complexity of Peyronie’s anatomy routinely.

Implant surgery carries real risks, and it is important to weigh them: infection, device malfunction and the possibility of revision surgery over time, erosion of the device, and — because the implant straightens a penis already shortened by scar tissue — a perceived loss of length compared with before the disease. Dr. Gheiler reviews these risks candidly, alongside the benefits, before you decide.